Childhood stroke and lupus anticoagulant

Pediatr Neurol. 1994 Feb;10(1):54-7. doi: 10.1016/0887-8994(94)90068-x.

Abstract

Despite extensive evaluation, the cause of many childhood ischemic strokes remains unexplained. Two children are reported with stroke and lupus anticoagulant. Both had family members with features of the antiphospholipid antibody syndrome. Children with unexplained ischemic stroke should be evaluated for lupus anticoagulant and anticardiolipin antibodies.

Publication types

  • Case Reports

MeSH terms

  • Antiphospholipid Syndrome / diagnosis
  • Antiphospholipid Syndrome / genetics*
  • Brain / pathology
  • Cerebrovascular Disorders / diagnosis
  • Cerebrovascular Disorders / genetics*
  • Child, Preschool
  • Humans
  • Lupus Coagulation Inhibitor / analysis*
  • Lupus Erythematosus, Systemic / diagnosis
  • Lupus Erythematosus, Systemic / genetics
  • Magnetic Resonance Imaging
  • Male
  • Phenotype
  • Tomography, X-Ray Computed

Substances

  • Lupus Coagulation Inhibitor