Patterned neural activity in brain stem auditory areas of a prehearing mammal, the tammar wallaby (Macropus eugenii)

Neuroreport. 1994 Feb 24;5(6):685-8. doi: 10.1097/00001756-199402000-00006.


Is patterned neural activity in immature, prefunctioning sensory systems a general phenomenon? Such patterning has been found in the prenatal visual and somatosensory systems. We have now identified patterning in the immature auditory system of a prehearing mammal, the tammar wallaby. Neurones recorded in vivo from the eighth nerve and cochlear nucleus at pouch days 94-122 discharged in bursts with rhythmic inter-spike intervals. Our findings are applied to the argument that neural activity is vital to sensory development.

MeSH terms

  • Acoustic Stimulation
  • Animals
  • Brain Stem / growth & development
  • Brain Stem / physiology*
  • Cochlear Nucleus / cytology
  • Cochlear Nucleus / growth & development
  • Cochlear Nucleus / physiology
  • Electrodes, Implanted
  • Evoked Potentials, Auditory, Brain Stem / physiology
  • Hearing / physiology*
  • Macropodidae / physiology*
  • Neurons / physiology*
  • Neurons, Afferent / physiology
  • Vestibulocochlear Nerve / cytology
  • Vestibulocochlear Nerve / growth & development
  • Vestibulocochlear Nerve / physiology