Hemangioma of the choroid. A clinicopathologic study of 71 cases and a review of the literature

Surv Ophthalmol. May-Jun 1976;20(6):415-31. doi: 10.1016/0039-6257(76)90067-9.

Abstract

This is a clinicopathologic study of 71 hemangiomas of the choroid. The cases were divided into three groups: Group 1 consisted of 45 cases of solitary choroidal hemangiomas (not related to any systemic disease); Group 2 comprised 17 cases with unequivocal evidence of Sturge-Weber syndrome; and Group 3 included 9 cases, 6 of which were classified as "probably Sturge-Weber syndrome." Clinically, many differences were found that established a clear distinction between Groups 1 and 2. Histopathologically, the solitary hemangiomas were well-circumscribed tumors that showed a sharply demarcated pushing margin causing compression of melanocytes and choroidal lamellae. About 70% of these tumors were located temporally (at the posterior pole). In contrast, the lesions in the Sturge-Weber syndrome showed a diffuse angiomatosis involving more than one-half of the choroid, as well as the episcleral and intrascleral perilimbal plexuses. The cause and pathogenesis of these lesions are discussed.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Age Factors
  • Angiomatosis / pathology*
  • Child
  • Choroid / pathology*
  • Choroid Neoplasms / pathology*
  • Female
  • Glaucoma / congenital
  • Hemangioma / pathology*
  • Hemangioma / surgery
  • Humans
  • Infant
  • Infant, Newborn
  • Ophthalmoscopy
  • Optic Disk / pathology
  • Ossification, Heterotopic / pathology
  • Retina / pathology
  • Retinitis Pigmentosa / pathology
  • Sex Factors
  • Sturge-Weber Syndrome / pathology
  • Visual Fields