[Influence of chloride ions on the kinetic parameters of rat brain choline acetyltransferase]

C R Acad Hebd Seances Acad Sci D. 1976 May 3;282(17):1621-4.
[Article in French]

Abstract

Kinetic properties of Rat brain choline acetyltransferase were studied. Chloride ions promoted the increase of the Km values for the two substrates. Vmax was increased sixty times when chloride ions concentration was elevated from 4.6 to 291 mM.

Publication types

  • English Abstract

MeSH terms

  • Acetylcholine / biosynthesis
  • Acetyltransferases / metabolism*
  • Animals
  • Brain / enzymology
  • Chlorides / pharmacology*
  • Choline O-Acetyltransferase / metabolism*
  • Kinetics
  • Rats

Substances

  • Chlorides
  • Acetyltransferases
  • Choline O-Acetyltransferase
  • Acetylcholine