Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors

J Urol. 1976 Aug;116(2):180-3. doi: 10.1016/s0022-5347(17)58737-6.


Patients with recurrent superficial bladder tumors have been treated by vesical and intradermal administration of Bacillus Calmette-Guerin. The pattern of recurrence in 9 patients has been altered favorably. Although the findings are still preliminary they appear to hold promise of a new therapeutic approach to the treatment of a group of neoplasms for which effective therapy is still lacking.

MeSH terms

  • Aged
  • BCG Vaccine*
  • Carcinoma, Transitional Cell / immunology
  • Carcinoma, Transitional Cell / therapy*
  • Female
  • Humans
  • Hypersensitivity, Delayed
  • Immunotherapy
  • Leukocyte Count
  • Lymphocytes / immunology
  • Male
  • Middle Aged
  • Mycobacterium bovis / immunology*
  • Neoplasm Recurrence, Local
  • Thiotepa / therapeutic use
  • Urinary Bladder Neoplasms / immunology
  • Urinary Bladder Neoplasms / therapy*


  • BCG Vaccine
  • Thiotepa