The visual-evoked response in infants with central visual impairment

Am J Ophthalmol. 1993 Oct 15;116(4):437-43. doi: 10.1016/s0002-9394(14)71401-1.


We studied ten children with central visual impairment with a known neurologic defect and an abnormal visual-evoked response who had results of repeat electrophysiologic testing evaluated at the Children's Hospital of Philadelphia from December 1989 through July 1991. Central visual impairment is defined as poor visual function with a normal anterior visual pathway. Age at first examination ranged from 5 to 48 months with a followup of two to 31 months. Repeat visual-evoked response testing showed improvement in seven patients and no change in three. Grating acuity as measured by the Teller acuity card procedure, performed in nine of ten patients, improved in seven, showed no change in one, and declined in one. We found a potentially favorable prognosis for those infants with central visual impairment, despite an initially abnormal visual-evoked response. We used a clinical approach to this disorder to improve diagnostic categorization and prognostic capabilities in central visual impairment.

MeSH terms

  • Brain Diseases / physiopathology
  • Child, Preschool
  • Electroretinography
  • Evoked Potentials, Visual*
  • Follow-Up Studies
  • Humans
  • Infant
  • Light
  • Prognosis
  • Vision Disorders / physiopathology*
  • Visual Acuity