B19 parvovirus-induced anemia in a normal child. Initial bone marrow erythroid hyperplasia and response to intravenous immunoglobulin

Am J Pediatr Hematol Oncol. 1993 Nov;15(4):420-3.


Purpose: Human B19 parvovirus infection may cause severe erythroid hypoplasia in patients with an underlying hemolytic anemia. We report a case of severe parvovirus-induced anemia with initial marrow erythroid hyperplasia in a child with no underlying hematologic disorder.

Conclusions: The patient's rapid hemoglobin recovery after treatment with i.v. immunoglobulin further supports this form of therapy for children with parvovirus-induced anemia.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anemia / blood
  • Anemia / etiology*
  • Anemia / pathology
  • Bone Marrow / pathology*
  • Child
  • Erythema Infectiosum / blood
  • Erythema Infectiosum / complications*
  • Erythema Infectiosum / pathology
  • Erythrocytes / drug effects
  • Erythrocytes / pathology*
  • Hematopoietic Stem Cells / pathology
  • Hemoglobins / metabolism
  • Humans
  • Hyperplasia
  • Immunoglobulins, Intravenous / therapeutic use*
  • Male
  • Parvovirus B19, Human*


  • Hemoglobins
  • Immunoglobulins, Intravenous