Using pyridoxine to treat carpal tunnel syndrome. Randomized control trial

Can Fam Physician. 1993 Oct;39:2122-7.

Abstract

In this study, we examined prospectively the effect of pyridoxine on idiopathic carpal tunnel syndrome. Thirty-two patients with the disease were randomized to receive treatment or placebo. No differences in outcome were found in electrophysiologic signs, clinical signs, or significant symptoms. Our findings do not support the use of pyridoxine for treating carpal tunnel syndrome.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aspartate Aminotransferases / blood
  • Carpal Tunnel Syndrome / drug therapy*
  • Carpal Tunnel Syndrome / physiopathology
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Median Nerve / physiopathology
  • Middle Aged
  • Motor Neurons / physiology
  • Neural Conduction / physiology
  • Patient Compliance
  • Placebos
  • Pyridoxal Phosphate / blood
  • Pyridoxine / administration & dosage
  • Pyridoxine / blood
  • Pyridoxine / therapeutic use*
  • Reaction Time / physiology

Substances

  • Placebos
  • Pyridoxal Phosphate
  • Aspartate Aminotransferases
  • Pyridoxine