Circulatory effects of vasoconstrictors combined with local anesthetics

Anesth Pain Control Dent. Spring 1993;2(2):81-6.

Abstract

Vasoconstrictors are clinically used as adjuvants to local anesthetics to improve anesthetic action and to minimize local bleeding. Accidental intravascular injection or rapid systemic absorption of vasoconstrictors can induce a number of potentially life-threatening circulatory risks, which are described in this paper.

Publication types

  • Review

MeSH terms

  • Anesthesia, Dental* / adverse effects
  • Anesthetics, Local / pharmacokinetics
  • Anesthetics, Local / pharmacology*
  • Contraindications
  • Dental Care for Chronically Ill
  • Drug Combinations
  • Drug Interactions
  • Epinephrine / pharmacology
  • Hemodynamics / drug effects*
  • Humans
  • Lidocaine / pharmacology
  • Mepivacaine / pharmacology
  • Norepinephrine / pharmacology
  • Vasoconstrictor Agents / pharmacology*

Substances

  • Anesthetics, Local
  • Drug Combinations
  • Vasoconstrictor Agents
  • Lidocaine
  • Mepivacaine
  • Norepinephrine
  • Epinephrine