[Alkalizing activity of a calcium-bicarbonate-containing water, evaluated for pH, in patients with gastroesophageal reflux]

Clin Ter. 1993 Aug;143(2):131-6.
[Article in Italian]


Bicarbonate-calcic water Ferrarelle has been administered both in the fasting state and during meals to patients suffering from gastro-esophageal reflux disease submitted to computerized pHmetry. Marked and lasting increase of esophageal and gastric pH was observed with significant differences from the effect of tap water. In addition, patients reported improvement of heart burn and acidity after the administration of the bicarbonate-calcic water. The alkalizing effect of the mineral water employed is therefore fully confirmed.

Publication types

  • English Abstract

MeSH terms

  • Alkalies / therapeutic use
  • Bicarbonates / therapeutic use*
  • Female
  • Gastroesophageal Reflux / therapy*
  • Humans
  • Hydrogen-Ion Concentration
  • Male
  • Mineral Waters*


  • Alkalies
  • Bicarbonates
  • Mineral Waters
  • calcium bicarbonate