Bacterial Adherence to Hydrophilic Polymer-Coated Polyurethane Stents

Gastrointest Endosc. Sep-Oct 1993;39(5):670-3. doi: 10.1016/s0016-5107(93)70220-5.

Abstract

Biliary stent blockage by adherence of bacteria and formation of biofilm is a major problem in endoscopic stenting procedures. We have investigated bacterial adherence to hydrophilic polymer (Hydromer)-coated polyurethane stents in stationary and perfusion experiments. Adherence of gram negative and gram positive organisms under stationary conditions was similar between Hydromer-coated and non-coated control polyurethane stents; however, a marked 1 to 3 log reduction in adherence to Hydromer-coated stents occurred when perfusion experiments in phosphate buffer solution or bile were performed. The results suggest that Hydromer-coated polyurethane stents could be useful in preventing complications caused by biliary stent blockage.

Publication types

  • Comparative Study

MeSH terms

  • Bacterial Adhesion / physiology*
  • Enterococcus faecalis / physiology
  • Escherichia coli / physiology
  • Humans
  • Isocyanates*
  • Klebsiella / physiology
  • Polyurethanes*
  • Povidone / analogs & derivatives*
  • Proteus mirabilis / physiology
  • Stents* / adverse effects

Substances

  • Isocyanates
  • Polyurethanes
  • hydromer
  • Povidone