Reproducibility of topometric data acquisition in normal and glaucomatous optic nerve heads with the laser tomographic scanner

Graefes Arch Clin Exp Ophthalmol. 1993 Aug;231(8):457-64. doi: 10.1007/BF02044232.


The reproducibility of optic disc cup measurements was analyzed in 24 eyes of 24 patients [8 normals, 8 glaucoma patients, 8 glaucoma suspects] using the Laser Tomographic Scanner. The mean coefficient of variation in triple measurements was 5.0% for the cup area, 5.4% for the rim area, 7.0% for the cup volume, 4.0% for the mean cup depth, and 4.3% for the maximum cup depth. Mean reliability between two of the three measurements performed in each eye was better than 0.988 for the cup area, 0.995 for the cup volume and 0.996 for the mean cup depth readings. These results suggest that laser scanning tomography allows highly reproducible measurements in living eyes and adds an important tool to the ophthalmologist's armamentarium for the diagnosis and follow-up of glaucoma patients.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Female
  • Glaucoma / pathology*
  • Humans
  • Image Processing, Computer-Assisted
  • Lasers
  • Male
  • Middle Aged
  • Ocular Hypertension / pathology
  • Optic Disk / pathology*
  • Optic Nerve Diseases / pathology*
  • Random Allocation
  • Reference Values
  • Reproducibility of Results