A case of acrogeria

J Dermatol. 1993 Sep;20(9):572-6. doi: 10.1111/j.1346-8138.1993.tb01341.x.

Abstract

We report a 30-year-old Japanese male with acrogeria. He was in good health except for the prominent skin atrophy over the hands and feet. In the microscopic view of an atrophic skin biopsy specimen, elastic fibers were clumped and fragmented, especially in the upper dermis. Reviewing fourteen previously reported Japanese cases of acrogeria, the decrease and degeneration of elastic fibers were the prominent characteristic, as was the atrophy of subcutaneous fat.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Atrophy
  • Child
  • Female
  • Foot
  • Hand
  • Humans
  • Male
  • Middle Aged
  • Skin / pathology*
  • Skin Aging*