Initial cross-sectional results from the Orinda Longitudinal Study of Myopia

Optom Vis Sci. 1993 Sep;70(9):750-8. doi: 10.1097/00006324-199309000-00012.


Background: Although investigations of human refractive error development and normal ocular growth have been conducted for the last 50 years, no previous study of refractive error and the ocular components has measured all the ocular components.

Methods: The Orinda Longitudinal Study of Myopia was initiated to characterize the development of refractive error and normal eye growth in a sample of predominantly Caucasian children ages 6 to 14 years.

Results: Cross-sectional results from 530 children ages 5 to 12 years in the 1st, 3rd, and 6th grades are presented.

Conclusions: This sample's refractive error decreased toward emmetropia with age from an average of +0.73 D at age 6 years to an average of +0.50 D by age 12 years. Between the ages of 6 and 12 years, the vitreous chamber elongated (by 0.52 mm) and the crystalline lens power decreased (by 1.35 D); surprisingly, the crystalline lens thinned by 0.14 mm during this same time period.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • California
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Eye / growth & development
  • Female
  • Follow-Up Studies
  • Humans
  • Longitudinal Studies
  • Male
  • Myopia / etiology*
  • Myopia / physiopathology
  • Ocular Physiological Phenomena
  • Risk Factors