Bronchiolitis obliterans organizing pneumonia and rheumatoid arthritis

Semin Arthritis Rheum. 1993 Aug;23(1):70-8. doi: 10.1016/s0049-0172(05)80027-7.


The case of a 68-year-old woman who presented with dyspnea and upper lobe pulmonary infiltrates and shortly thereafter developed seropositive, erosive polyarticular rheumatoid arthritis (RA) is presented. An open-lung biopsy to evaluate progression of infiltrates showed bronchiolitis obliterans-organizing pneumonia (BOOP). Both lung and articular disease responded rapidly to corticosteroid therapy. Interrelationships between BOOP, bronchiolitis obliterans, and interstitial fibrosis with connective tissue disease are discussed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Arthritis, Rheumatoid / diagnostic imaging
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / etiology*
  • Bronchiolitis Obliterans / complications*
  • Bronchiolitis Obliterans / diagnostic imaging
  • Bronchiolitis Obliterans / drug therapy
  • Female
  • Humans
  • Pneumonia / complications*
  • Pneumonia / diagnostic imaging
  • Pneumonia / drug therapy
  • Prednisone / therapeutic use
  • Radiography


  • Prednisone