Phage type of tubercle bacilli isolated from patients with two or more sites of organ involvement

Am Rev Respir Dis. 1976 Aug;114(2):353-8. doi: 10.1164/arrd.1976.114.2.353.


To evaluate the possibility of separate pulmonary infections in human beings by different strains of Mycobacterium tuberculosis, a search for multiple phage types within a single host was under-taken. Culture isolates from 2 or more distinct anatomic sites of infection in the same patient were obtained from 87 persons. In 3 subjects, 2 distinct phage types were found. The possible explanations for 2 types in the same patient and the epidemiologic implications are discussed.

MeSH terms

  • Adult
  • Bacteriophage Typing*
  • Female
  • Humans
  • Lymph Nodes / microbiology
  • Male
  • Middle Aged
  • Mycobacteriophages / isolation & purification*
  • Mycobacterium tuberculosis / isolation & purification*
  • Pleural Effusion / microbiology
  • Sputum / microbiology
  • Tuberculosis, Miliary / microbiology
  • Tuberculosis, Pulmonary / microbiology*
  • Urine / microbiology