Congenital cytomegalovirus infection presenting as cerebral ventriculomegaly on antenatal sonography

Am J Perinatol. 1993 Sep;10(5):404-6. doi: 10.1055/s-2007-994773.

Abstract

Antenatal sonography in two cases demonstrated cerebral ventriculomegaly and decreased head circumference, subsequently found to be secondary to cytomegalovirus (CMV) infection. In both cases, the lateral ventricles were enlarged and lissencephaly was diagnosed in the neonatal period. The findings of ventriculomegaly and decreased head circumference on antenatal sonography warrant further investigation for CMV via amniotic fluid cultures or fetal blood, given the poor prognosis in infants with symptomatic infection.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Brain Diseases / congenital*
  • Brain Diseases / diagnostic imaging
  • Brain Diseases / pathology
  • Cerebral Ventricles / abnormalities*
  • Cerebral Ventricles / diagnostic imaging
  • Cerebral Ventricles / pathology
  • Cytomegalovirus Infections / congenital*
  • Cytomegalovirus Infections / diagnostic imaging
  • Diagnosis, Differential
  • Female
  • Fetal Diseases / diagnostic imaging*
  • Fetal Diseases / pathology
  • Humans
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Necrosis
  • Pregnancy
  • Pregnancy Trimester, Second
  • Ultrasonography, Prenatal*
  • Urine / microbiology