Is chronic graft versus host disease an autoimmune disease?

Curr Opin Immunol. 1993 Oct;5(5):800-3. doi: 10.1016/0952-7915(93)90140-n.

Abstract

Chronic graft versus host disease continues to be a major problem following bone marrow transplantation even though the incidence and severity of acute graft versus host disease has been reduced. Recent investigations have suggested that the pathogenesis of chronic graft versus host disease is more similar clinically to an autoimmune disease than to acute graft versus host disease.

Publication types

  • Review

MeSH terms

  • Animals
  • Autoimmune Diseases / immunology*
  • Autoimmunity / immunology
  • Bone Marrow Transplantation / adverse effects
  • Bone Marrow Transplantation / immunology
  • Chronic Disease
  • Cyclosporine / immunology
  • Disease Models, Animal
  • Graft vs Host Disease / immunology*
  • Humans
  • Mice

Substances

  • Cyclosporine