The structural and functional analysis of cadherin calcium-dependent cell adhesion molecules

Curr Opin Cell Biol. 1993 Oct;5(5):797-805. doi: 10.1016/0955-0674(93)90028-o.


During the past year considerable progress has been made in our understanding of cadherin structure and function. Recent research has concentrated on several aspects of the cell and molecular biology of cadherins, including genomic organization, cytoskeletal interactions, regulation of expression and function by post-translational modifications, differential expression during embryonic development, and the emerging role of cadherin misexpression and malfunction in pathogenesis.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Cadherins / biosynthesis
  • Cadherins / genetics
  • Cadherins / physiology*
  • Calcium / metabolism
  • Calcium / physiology*
  • Cytoskeleton / physiology
  • Gene Expression Regulation
  • Humans
  • Protein Processing, Post-Translational


  • Cadherins
  • Calcium