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Case Reports
. 1993 Oct;8(8):277-80.

[Neurologic Complications Induced by the Treatment of the Acute Renal Allograft Rejection With the Monoclonal Antibody OKT3]

[Article in Spanish]
Affiliations
  • PMID: 8240843
Case Reports

[Neurologic Complications Induced by the Treatment of the Acute Renal Allograft Rejection With the Monoclonal Antibody OKT3]

[Article in Spanish]
O Fernández et al. Neurologia. .

Abstract

The treatment of the acute renal allograft rejection with the monoclonal antibody orthoclone OKT3 produces both systemic and neurologic alterations. In a series of 21 patients with an acute renal allograft rejection treated with this monoclonal antibody, 20 with a renal allograft transplantation and one with a renal and pancreatic allograft transplantation, 29% referred headache associated with fever and vomiting, and 14.2% presented severe neurological alterations induced by the treatment. We stress the need to know these secondary effects to differentiate them from other central nervous system disorders, particularly those of infectious origin.

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