Structure of the human progesterone receptor gene

Biochim Biophys Acta. 1993 Nov 16;1216(2):289-92. doi: 10.1016/0167-4781(93)90156-8.


The complete organization of the human progesterone receptor (hPR) gene has been determined. It spans over 90 kbp and contains eight exons. The first exon encodes the N-terminal part of the receptor. The DNA binding domain is encoded by two exons, each exon corresponding to one zinc finger. The steroid binding domain is encoded by five exons. The nucleotide sequence of 1144 bp of the 5' flanking region has been determined.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Exons*
  • Humans
  • Introns
  • Molecular Sequence Data
  • Promoter Regions, Genetic
  • Receptors, Progesterone / genetics*


  • Receptors, Progesterone

Associated data

  • GENBANK/L08443
  • GENBANK/X69068
  • GENBANK/X69069
  • GENBANK/X69070
  • GENBANK/X69071
  • GENBANK/X69072
  • GENBANK/X69073
  • GENBANK/X69074
  • GENBANK/X69075
  • GENBANK/X69076