Mutational approaches to studying embryonic pattern formation in the zebrafish

Curr Opin Genet Dev. 1993 Aug;3(4):648-54. doi: 10.1016/0959-437x(93)90102-u.


The induction and isolation of mutations in genes playing important roles in pattern formation have been extremely valuable in elucidating the mechanisms governing pattern formation in invertebrates. The recent establishment of genetic methods in the zebrafish, Brachydanio rerio, has permitted systematic mutational studies of vertebrate embryonic development.

Publication types

  • Review

MeSH terms

  • Animals
  • Mutagenesis*
  • Mutagens / toxicity
  • Zebrafish / embryology*
  • Zebrafish / genetics


  • Mutagens