Control of vertebrate gastrulation: inducing signals and responding genes

Curr Opin Genet Dev. 1993 Aug;3(4):655-61. doi: 10.1016/0959-437x(93)90103-v.


Recently, genes with similar expression patterns in the early gastrulae of several different vertebrate species have been identified. The remarkable conservation of these expression patterns suggests that fundamental similarities exist within the vertebrates at remarkably early stages. It has yet to be established exactly how these genes are activated in the correct spatial patterns and what their functions might be.

Publication types

  • Review

MeSH terms

  • Animals
  • Embryonic Induction / physiology
  • Gastrula / physiology*
  • Gene Expression Regulation
  • Mesoderm
  • Signal Transduction
  • Vertebrates / embryology*
  • Vertebrates / genetics