Comparison of the waveforms of the ON bipolar neuron and the b-wave of the electroretinogram

Vision Res. 1993 Dec;33(17):2431-5. doi: 10.1016/0042-6989(93)90122-d.


The b-wave of the electroretinogram (ERG) is believed to result largely from the light responses of ON bipolar neurons. One apparent inconsistency is that the b-wave is a phasic signal, more similar to ON responses of transient third-order neurons than to the ON bipolar light responses. However, when selective glutamate agonists or antagonists were used to isolate the b-wave, it was found to be tonic and resemble the light response waveform of the ON bipolar cell.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Ambystoma
  • Aminobutyrates / pharmacology
  • Animals
  • Electroretinography / drug effects
  • In Vitro Techniques
  • Neurons / physiology
  • Photic Stimulation
  • Retina / physiology*


  • Aminobutyrates
  • 2-amino-4-phosphonobutyric acid