Norpethidine toxicity and patient controlled analgesia

Br J Anaesth. 1993 Nov;71(5):738-40. doi: 10.1093/bja/71.5.738.

Abstract

Patient-controlled analgesia (PCA) with i.v. opioids is prescribed increasingly. We report three cases of norpethidine toxicity in patients receiving pethidine by PCA.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Analgesia, Patient-Controlled*
  • Cholinesterase Inhibitors / adverse effects*
  • Cholinesterase Inhibitors / blood
  • Female
  • Humans
  • Meperidine / adverse effects*
  • Meperidine / analogs & derivatives*
  • Meperidine / blood
  • Meperidine / therapeutic use
  • Middle Aged
  • Pain, Postoperative / drug therapy

Substances

  • Cholinesterase Inhibitors
  • Meperidine
  • normeperidine