Evaluation of Delayed Puberty in the Female Adolescent With Chronic Renal Failure

Pediatr Nephrol. 1993 Oct;7(5):551-3. doi: 10.1007/BF00852544.


The purpose of this report is to discuss the differential diagnosis of delayed puberty in the adolescent female with chronic renal failure. The appropriate therapy varies depending on the etiology of the delay. Frasier syndrome--chronic renal failure with true gonadal dysgenesis--should be considered in the diagnosis of a normal phenotypic female with end-stage renal disease and delayed puberty.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Diagnosis, Differential
  • Evaluation Studies as Topic
  • Female
  • Gonadal Dysgenesis / complications
  • Humans
  • Hypogonadism / complications
  • Karyotyping
  • Kidney Failure, Chronic / complications*
  • Puberty, Delayed / diagnosis*
  • Puberty, Delayed / etiology