Experimental pyelonephritis in the monkey. IV. Vesicoureteral reflux and bacteria

Invest Urol. 1976 Nov;14(3):198-201.


A model was designed to study the relation between urinary infection and vesicoureteral, low-grade, total reflux. Surgical alteration of the ureterovesical junction produced grade 2 vesicoureteral reflux in seven of 13 animals. In the other six animals, surgery had rendered the vesicoureteral junction marginally competent and chronic bladder infection caused grade 2 reflux. It was found that grade 2 vesicoureteral reflux in the adult monkey neither prolongs urinary tract infection nor causes continued renal infection.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Disease Models, Animal*
  • Escherichia coli Infections / complications*
  • Female
  • Foreign Bodies / complications
  • Haplorhini
  • Macaca
  • Oxalates
  • Proteus Infections / complications*
  • Proteus mirabilis
  • Pyelonephritis / chemically induced
  • Pyelonephritis / etiology*
  • Urinary Bladder / surgery
  • Vesico-Ureteral Reflux / complications*


  • Oxalates