Fast proton spectroscopic imaging of human brain using multiple spin-echoes

Magn Reson Med. 1993 Oct;30(4):409-14. doi: 10.1002/mrm.1910300403.


We introduce a multi-echo multi-slice MR proton spectroscopic imaging method, which allows for a dramatic reduction of the measurement time by acquiring multiple spin-echoes within a single repetition time. In the multi-echo multi-slice experiment discussed in this paper, a threefold reduction in measurement time is obtained by sacrificing some spectral resolution. Signal-to-noise ratio and spatial resolution are preserved. Metabolite images of N-acetyl aspartate, and total choline+total creatine from multiple slices through the human brain are presented and compared with images obtained with a conventional single-echo multi-slice method.

MeSH terms

  • Brain / anatomy & histology*
  • Brain / metabolism
  • Humans
  • Magnetic Resonance Spectroscopy / methods
  • Protons


  • Protons