The release, absorption and possible health effects of mercury from dental amalgam: a review of recent findings

Br Dent J. 1993 Nov 20;175(10):355-62. doi: 10.1038/sj.bdj.4808325.


Recently many articles have appeared on the subject of mercury from dental amalgam and some of these have questioned its safety as a dental material. This article reviews critically the evidence on mercury release from dental amalgam restorations, its absorption, accumulation and excretion by the body, and its possible relationship to ill-effects. Finally, brief recommendations are given for the handling and usage of dental amalgam.

Publication types

  • Corrected and Republished Article
  • Review

MeSH terms

  • Abnormalities, Drug-Induced / etiology
  • Body Burden
  • Dental Amalgam / adverse effects*
  • Dental Restoration, Permanent / adverse effects
  • Dental Waste
  • Fetal Death / chemically induced
  • Humans
  • Hypersensitivity / etiology
  • Immunocompetence / drug effects
  • Kidney Diseases / chemically induced
  • Mercury / adverse effects*
  • Mercury / pharmacokinetics*
  • Mercury Poisoning / complications
  • Mercury Poisoning / etiology
  • Multiple Sclerosis / chemically induced
  • Tissue Distribution


  • Dental Waste
  • Dental Amalgam
  • Mercury