5-methoxyuridine: a new minor constituent located in the first position of the anticodon of tRNAAla, tRNAThr, and tRNAVal from Bacillus subtilis

Nucleic Acids Res. 1976 Oct;3(10):2851-60. doi: 10.1093/nar/3.10.2851.

Abstract

The sequences of the anticodon of tRNAAla, tRNAThr, and tRNAVal from Bacillus subtilis W 168 were N-G-C, N-G-U, and N-A-C, respectively. A new minor constituent, N, occupied the first position of the anticodon of each tRNA. N was indentified as 5-methoxyuridine (mo5U, Figure 1) by comparison of its UV absorption spectra, Rf values in thin-layer chromatography using several solvent systems and mass spectra with those of chemically synthesized specimen.

MeSH terms

  • Alanine
  • Anticodon*
  • Bacillus subtilis / analysis*
  • Base Sequence
  • RNA, Bacterial*
  • RNA, Transfer*
  • Threonine
  • Uridine / analogs & derivatives*
  • Uridine / analysis
  • Valine

Substances

  • Anticodon
  • RNA, Bacterial
  • Threonine
  • RNA, Transfer
  • Valine
  • Alanine
  • Uridine