Multidisciplinary teamwork or collaboration is a new approach designed to guide thinking and practise within healthcare systems. As a concept multidisciplinary collaboration or teamwork is not clear. Researchers have developed many definition about multidisciplinary collaboration having characteristics like objectivity, methodicalness, regularity, common goals, population's/patient's perspective and individually shared responsibility. In decision making every expert has a responsibility to give his/her skills and acknowledge for the goals of the working community and patients. A great deal of research and development work is currently ongoing in hospitals and health centers on multidisciplinary topic. This approach has been useful in district responsibility and also in primary nursing. The leadership in primary nursing system has the responsibility to create an environment conductive for collaborative relationships. In multiprofessional relationships nurses can find their professional roles and evaluate their skills and knowledge base and assess their needs for continued education.