Rapid smoking of menthol and nonmenthol cigarettes by black and white smokers

Pharmacol Biochem Behav. 1993 Oct;46(2):259-63. doi: 10.1016/0091-3057(93)90350-3.


White subjects took significantly more puffs of cigarette smoke before stopping than did black subjects in a modified, controlled-dose rapid smoking procedure. Paradoxically, however, no racial differences were detected for changes in carbon monoxide levels, or changes in cardiovascular variables (systolic and diastolic blood pressure, and heart rate). Due to the cooling and topical anesthetic properties of menthol, it was hypothesized that menthol and regular cigarette smokers would take more puffs from menthol cigarettes than from regular cigarettes before stopping in the controlled-dose rapid smoking procedure. However, no difference was observed for the number of puffs taken from regular as opposed to menthol cigarettes (cigarette type condition) and no differences were found for Cigarette Preference (regular smokers vs. menthol smokers).

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • African Continental Ancestry Group
  • Blood Pressure / drug effects
  • Carbon Monoxide / blood
  • European Continental Ancestry Group
  • Female
  • Heart Rate / drug effects
  • Humans
  • Male
  • Menthol / pharmacology*
  • Smoking / physiopathology
  • Smoking / psychology*


  • Menthol
  • Carbon Monoxide