Do topical antibiotics help corneal epithelial trauma?

Can Fam Physician. 1993 Nov:39:2349-52.

Abstract

Topical antibiotics are routinely used in emergency rooms to treat corneal trauma, although no published evidence supports this treatment. In a noncomparative clinical trial, 351 patients with corneal epithelial injuries were treated without antibiotics. The infection rate was 0.7%, suggesting that such injuries can be safely and effectively managed without antibiotics. A comparative clinical trial is neither warranted nor feasible.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Topical
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Corneal Diseases / epidemiology*
  • Corneal Diseases / etiology
  • Corneal Diseases / prevention & control
  • Corneal Injuries*
  • Emergency Service, Hospital
  • Female
  • Humans
  • Infant
  • Infections / epidemiology*
  • Infections / etiology
  • Male
  • Middle Aged
  • Prospective Studies
  • Wounds and Injuries / complications
  • Wounds and Injuries / drug therapy

Substances

  • Anti-Bacterial Agents