Use of chemical clamps in denaturing gradient gel electrophoresis: application in the detection of the most frequent Mediterranean beta-thalassemic mutations

PCR Methods Appl. 1993 Oct;3(2):122-4. doi: 10.1101/gr.3.2.122.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Base Sequence
  • DNA / blood*
  • DNA / isolation & purification
  • DNA Primers
  • Electrophoresis, Polyacrylamide Gel / methods
  • Exons
  • Genetic Carrier Screening
  • Globins / genetics*
  • Hemoglobins / genetics
  • Humans
  • Molecular Sequence Data
  • Point Mutation*
  • Polymerase Chain Reaction / methods
  • beta-Thalassemia / blood
  • beta-Thalassemia / genetics*

Substances

  • DNA Primers
  • Hemoglobins
  • Globins
  • DNA