Synthetic enhancement in gene interaction: a genetic tool come of age

Trends Genet. 1993 Oct;9(10):362-6. doi: 10.1016/0168-9525(93)90042-g.


Synthetic enhancement, in which one mutation exacerbates the severity of another, is a genetic interaction of increasing importance in biology. This review focuses on the logic of interpreting synthetic enhancement, and begins by comparing the phenomenon with genetic suppression.

Publication types

  • Review

MeSH terms

  • Animals
  • Mutation*
  • Suppression, Genetic*