Ranitidine-induced bradycardia in a neonate--a first report

Eur J Pediatr. 1993 Nov;152(11):933-4. doi: 10.1007/BF01957535.


Bradycardia, an extremely rare side-effect of ranitidine therapy is described in a 4-day-old full-term male neonate, who was admitted because of massive gastro-intestinal bleeding. Two hours after the intravenous injection of 1 mg/kg body weight per day, ECG showed sinus bradycardia of 60 beats/min with normal axis and QRS complex. The bradycardia gradually resolved in the next 24 h.

Publication types

  • Case Reports

MeSH terms

  • Bradycardia / chemically induced*
  • Gastrointestinal Hemorrhage / drug therapy
  • Humans
  • Infant, Newborn
  • Male
  • Ranitidine / adverse effects*
  • Ranitidine / therapeutic use


  • Ranitidine