The model of experimental alkali burn of cornea in rabbit was obtained using 1 mol/L NaOH solution. After being burned for 1, 3, 7 and 14 days, the histochemical changes of these models were studied by using labelled concanavalin A (ConA-FITC) and wheat germ agglutinin (WGA-FITC). The results showed that after being burned, the amount of glycoconjugates interacted with these lectins decreased, and increased gradually after 7 days, then reached the level higher than that in the normal cornea. These changes were related to the recovery of alkali burned cornea.