Induction of mutations in B. subtilis phage SPP1 by growth on host cells carrying a mutator DNA polymerase III

Mol Gen Genet. 1976 Dec 8;149(2):131-4. doi: 10.1007/BF00332880.


Phage SPP1 infecting a mutator strain of B. subtilis (BD337) which carries a defective DNA polymerase III is mutagenized. This effect is absent in phages SPO2, SP82G and øe. The results confirm previous observations that SPP1 uses host DNA polymerase III for its DNA synthesis.

MeSH terms

  • Bacillus subtilis / enzymology*
  • Bacteriophages*
  • DNA Polymerase III / metabolism*
  • DNA Replication
  • DNA, Viral / biosynthesis*
  • DNA-Directed DNA Polymerase / metabolism*
  • Mutation
  • Transformation, Genetic


  • DNA, Viral
  • DNA Polymerase III
  • DNA-Directed DNA Polymerase