Choroidal melanomas near the optic disk or macula. Long-term results after proton beam irradiation: a report of 3 cases

Ophthalmologica. 1993;206(1):18-23. doi: 10.1159/000310356.


Three patients with choroidal melanomas of the posterior pole were treated with proton beam irradiation. One tumor was medium-sized, two were large-sized. Two of the three eyes were functionally single eyes. 60 CGE (cobalt gray equivalents) was delivered in 4 equal treatments during 4 consecutive days. The minimum follow-up period for each patients is 4 years, the average time 4.8 years. Functionally, we lost both eyes with the large-sized tumors owing to severe radiogenic side effects; the eye containing the largest tumor had to be enucleated after 48 months because of phthisis bulbi. No metastases have developed up to now.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Blindness / etiology
  • Choroid Neoplasms / pathology
  • Choroid Neoplasms / radiotherapy*
  • Eye Enucleation
  • Female
  • Follow-Up Studies
  • Humans
  • Longitudinal Studies
  • Macula Lutea / radiation effects
  • Male
  • Melanoma / pathology
  • Melanoma / radiotherapy*
  • Middle Aged
  • Optic Disk / radiation effects
  • Radiation Injuries / etiology
  • Radiotherapy / adverse effects