A mesenchymal chondrosarcoma of a child with the reciprocal translocation (11;22)(q24;q12)

Cancer Genet Cytogenet. 1993 Dec;71(2):144-7. doi: 10.1016/0165-4608(93)90020-m.


The reciprocal translocation (11;22)(q24;q12) was observed in a seven day culture from a mesenchymal chondrosarcoma of the bone, a tumor not characterized cytogenetically so far. We suggest that because of the presence of a similar cytogenetic abnormality, mesenchymal chondrosarcoma may belong to the wide group of "t(11;22)-small round cell tumors".

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Aneuploidy
  • Bone Neoplasms / classification
  • Bone Neoplasms / genetics*
  • Bone Neoplasms / ultrastructure
  • Chondrosarcoma, Mesenchymal / classification
  • Chondrosarcoma, Mesenchymal / genetics*
  • Chondrosarcoma, Mesenchymal / ultrastructure
  • Chromosome Aberrations
  • Chromosomes, Human, Pair 11 / ultrastructure*
  • Chromosomes, Human, Pair 22 / ultrastructure*
  • Humans
  • Male
  • Tibia*
  • Translocation, Genetic*