One man's poison

Lancet. 1978 Dec;2(8104-5):1367. doi: 10.1016/s0140-6736(78)91994-3.

Abstract

In an unrandomised uncontrolled study on boats and trains, capsules of flurazepam (30 mg) and temazepam (20 mg), when chewed, but not when swallowed whole (even with the ends pricked), gave a better night's sleep than 'Mandrax' (methaqualone 250 mg/diphenhydramine 50 mg) and a better night's sleep than nitrazepam 7.5 mg.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Capsules
  • Clinical Trials as Topic
  • Diphenhydramine / administration & dosage
  • Drug Combinations
  • Drug Evaluation
  • Flurazepam / administration & dosage
  • Humans
  • Methaqualone / administration & dosage
  • Nitrazepam / administration & dosage
  • Sleep / drug effects*
  • Temazepam / administration & dosage
  • Travel*

Substances

  • Capsules
  • Drug Combinations
  • Methaqualone
  • Diphenhydramine
  • Nitrazepam
  • Temazepam
  • Flurazepam