Annetocin: an oxytocin-related peptide isolated from the earthworm, Eisenia foetida

Biochem Biophys Res Commun. 1994 Jan 14;198(1):393-9. doi: 10.1006/bbrc.1994.1055.

Abstract

An oxytocin-vasopressin-related peptide, Cys-Phe-Val-Arg-Asn-Cys-Pro-Thr-Gly-NH2, was isolated from the lumbricid earthworm, Eisenia foetida and termed annectocin. Annetocin potentiated not only spontaneous contractions of the gut but also pulsatory contractions and bladder-shaking movement of the nephridia. Annetocin may be involved in osmoregulation of the animal through nephridial function.

Publication types

  • Comparative Study

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Biological Assay
  • Chromatography, High Pressure Liquid
  • Invertebrate Hormones / chemistry*
  • Invertebrate Hormones / isolation & purification
  • Invertebrate Hormones / pharmacology
  • Molecular Sequence Data
  • Muscle Contraction / drug effects
  • Muscle, Smooth / drug effects
  • Muscle, Smooth / physiology
  • Oligochaeta / physiology*
  • Oxytocin / chemistry*
  • Peptides, Cyclic / chemistry*
  • Peptides, Cyclic / isolation & purification
  • Peptides, Cyclic / pharmacology
  • Sequence Homology, Amino Acid

Substances

  • Invertebrate Hormones
  • Peptides, Cyclic
  • annetocin
  • Oxytocin