Moyamoya syndrome in a patient with Down syndrome presenting with chorea

Pediatr Neurol. Sep-Oct 1993;9(5):396-8. doi: 10.1016/0887-8994(93)90111-o.


An 11-year-old girl with Down syndrome is reported with moyamoya syndrome; she presented with chorea and mental regression, but had no hemiplegia or convulsions. Magnetic resonance imaging and magnetic resonance angiography were valuable for diagnosis of moyamoya syndrome. It is suggested that moyamoya syndrome be considered as a possible cause of involuntary movements in Down syndrome patients.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Chorea / diagnosis
  • Chorea / etiology*
  • Diagnosis, Differential
  • Down Syndrome / complications*
  • Female
  • Humans
  • Japan / epidemiology
  • Magnetic Resonance Imaging*
  • Moyamoya Disease / complications*
  • Moyamoya Disease / diagnosis
  • Moyamoya Disease / epidemiology
  • Moyamoya Disease / pathology