Warfarin-induced skin necrosis

Hematol Oncol Clin North Am. 1993 Dec;7(6):1291-300.


Warfarin-induced skin necrosis is a rare but potentially devastating complication of oral anticoagulation. In this article the historical, clinical, and pathophysiologic features of this hypercoagulable event are reviewed, and recommendations for prevention and treatment are discussed.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Necrosis
  • Skin Diseases / chemically induced*
  • Skin Diseases / pathology
  • Skin Diseases / prevention & control
  • Skin Diseases / therapy
  • Warfarin / adverse effects*
  • Warfarin / therapeutic use


  • Warfarin