Acute Hereditary Coproporphyria Induced by the androgenic/anabolic Steroid Methandrostenolone (Dianabol)

J Am Acad Dermatol. 1994 Feb;30(2 Pt 2):308-12. doi: 10.1016/s0190-9622(94)70029-x.

Abstract

Acute attacks of porphyria can be induced by certain drugs. We report a case of acute coproporphyria induced by methandrostenolone. This is the first report of acute porphyria induced by an androgenic, anabolic steroid.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Coproporphyrinogen Oxidase / blood
  • Coproporphyrins / analysis
  • Coproporphyrins / blood
  • Coproporphyrins / urine
  • Feces / chemistry
  • Humans
  • Male
  • Methandrostenolone / adverse effects*
  • Pedigree
  • Porphyrias, Hepatic / blood
  • Porphyrias, Hepatic / chemically induced*
  • Porphyrias, Hepatic / genetics
  • Porphyrias, Hepatic / urine
  • Uroporphyrinogen Decarboxylase / urine

Substances

  • Coproporphyrins
  • Methandrostenolone
  • Coproporphyrinogen Oxidase
  • Uroporphyrinogen Decarboxylase