Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Feb;151(2):195-8.
doi: 10.1176/ajp.151.2.195.

Temperament and Hypercortisolemia in Depression

Affiliations

Temperament and Hypercortisolemia in Depression

P R Joyce et al. Am J Psychiatry. .

Abstract

Objective: The authors examined the relationships among depression severity, melancholia, and cortisol level and the relationship between temperament, as measured with the Tridimensional Personality Questionnaire, and cortisol level.

Method: Morning and afternoon cortisol levels of 40 healthy comparison subjects and 96 patients with major depression were measured. The depressed patients were rated for depression severity and melancholia, and they completed the Tridimensional Personality Questionnaire.

Results: Temperament, especially dependence and extravagance, but not depressive symptoms, was the major determinant of the hypercortisolemia observed in the depressed patients.

Conclusions: For research in biological psychiatry to advance, more attention needs to be paid to the individual differences in biology that underlie any state-dependent biologic dysfunction.

Similar articles

See all similar articles

Cited by 4 articles

Publication types

LinkOut - more resources

Feedback