Concentric MR patterns in multiple sclerosis. Report of two cases

J Neuroradiol. 1993 Dec;20(4):252-7.
[Article in English, French]


We report two cases of multiple sclerosis with concentric patterns of demyelinated foci on MR images. These were compared with the pathological data of Balò's disease. The T2-weighted MR images displayed alternating high and low signal areas which probably corresponded to the concentric type of demyelination. Our two cases were characterized by their acute onset and their regression following corticosteroid therapy. This suggests that Balò's disease may be a transient disease and not always associated with a fatal course.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / pathology
  • Demyelinating Diseases / diagnosis
  • Demyelinating Diseases / pathology
  • Diffuse Cerebral Sclerosis of Schilder / diagnosis
  • Diffuse Cerebral Sclerosis of Schilder / pathology
  • Female
  • Humans
  • Magnetic Resonance Imaging* / methods
  • Male
  • Multiple Sclerosis / diagnosis*
  • Multiple Sclerosis / pathology