Gorham's disease involving the thoracic skeleton. Plain films and CT in two cases

Pediatr Radiol. 1993;23(7):543-4. doi: 10.1007/BF02012145.


Two cases of Gorham's disease (massive osteolysis, idiopathic osteolysis, vanishing bone disease) involving the thoracic skeleton are reported. Both patients were adolescent females with involvement of multiple ribs. Involvement of the thoracic spine and pleural effusions--unusual manifestations carrying a poor prognosis--were also present. The radiographic and computed tomographic appearances are included with discussion and review of this disease entity.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Female
  • Humans
  • Osteolysis, Essential / complications
  • Osteolysis, Essential / diagnostic imaging*
  • Pleural Effusion / diagnostic imaging
  • Pleural Effusion / etiology
  • Ribs / diagnostic imaging
  • Sternum / diagnostic imaging
  • Thoracic Diseases / diagnostic imaging*
  • Thoracic Vertebrae / diagnostic imaging
  • Tomography, X-Ray Computed*