Morning glory syndrome in children. Association with endocrine and central nervous system anomalies

Arch Ophthalmol. 1994 Feb;112(2):204-7. doi: 10.1001/archopht.1994.01090140080027.


Objective: To identify morning glory syndrome, an uncommon optic disc anomaly. Generally, it is an isolated ocular abnormality; however, some cranial facial and neurologic associations have been reported.

Patients: We herein report two patients with morning glory syndrome and associated pituitary dwarfism. In one patient, the pituitary insufficiency was secondary to compression of the pituitary gland by a basal encephalocele; in the second patient, causative factors were not identified.

Conclusions: Patients with morning glory syndrome should have a complete general physical examination and growth evaluation so that early recognition and treatment of the patient with pituitary dwarfism can occur.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / pathology
  • Child, Preschool
  • Dwarfism, Pituitary / pathology*
  • Encephalocele / complications
  • Female
  • Fundus Oculi
  • Humans
  • Hypopituitarism / etiology
  • Hypopituitarism / pathology*
  • Infant
  • Magnetic Resonance Imaging
  • Male
  • Optic Disk / abnormalities*
  • Optic Disk / pathology
  • Optic Nerve / abnormalities
  • Optic Nerve / pathology
  • Pituitary Function Tests
  • Syndrome