Linkage analysis in familial Alzheimer disease: description of the Duke and Boston data sets

Genet Epidemiol. 1993;10(6):361-4. doi: 10.1002/gepi.1370100605.


Familial Alzheimer diseases is a neurological disorder of adult onset. Three research centers have each contributed their families and genetic linkage data for combined analyses. The data from the Duke and Boston centers, comprising 73 pedigrees for whom numerous markers on chromosomes 19 and 21 were typed are described.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Aged
  • Alzheimer Disease / epidemiology
  • Alzheimer Disease / genetics*
  • Boston / epidemiology
  • Chromosomes, Human, Pair 19
  • Chromosomes, Human, Pair 21
  • Genetic Linkage*
  • Genetic Markers
  • Humans
  • Middle Aged
  • North Carolina / epidemiology
  • Pedigree


  • Genetic Markers